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cytosol, systems, beet root, called, cardiovascular system, understand, beats, cardiovascular health, effect, science, created, shiva, nitric oxide, people, beets, endothelial dysfunction, enzyme, research, body, compounds
Dr.SHIVA Ayyadurai 00:01
Hello everyone, this is Dr. Shiva Ayyadrai. Welcome to Dr. Shiva, Dr. Shiva Live. Today we’re going to be doing a follow up. In fact, I’m going to redo the beats the beat route analysis I did about beats and cardiovascular health that I did a couple weeks ago. But I was rushed a little bit, there were some sound issues. So I’m going to do it end to end because I had an interview right after it.
So I rushed at the end of part, I really felt I chipped you guys. So I want to redo it again. So this is going to be, as I just shared with you, this is going to be on beet root and cardiovascular health. And we’re going to do a site assault analysis. So we’ll wait for people to join. But that’s what we’re going to be doing. We’re going to be talking about beet root and cardiovascular health. Again, those of you who saw it last time, I’m going to do it a little more slowly.
We’re gonna have a little bit we had some sound issues, we’re going to do it a little bit better. I really hate doing these things in a haphazard way was the probably the first time I’ve done this, one of the side of self analysis where I didn’t feel that it was done to the quality I like so we’re going to do it again. So I hope you guys enjoy it. Good. We have people joining us from New Jersey, Luxembourg. Welcome. Great to have you from Luxembourg. Joanne Nugen.
We have D house from New Jersey. So wait for people to join. Thank you. So let’s, so as many of you know, when I do these analyses, we use a technology called cytosol. And cytosol really provides us an ability to really understand these things at a very fundamental level from a systems analysis. So today’s talk, we’re gonna focus on beet root and cardiovascular health.
I’ll give you an overview, then we’re going to walk through what a systems approach means we’ll take a little break to talk about that, and how you guys can also learn systems approaches. We’ll talk about how beet root affects all different aspects of cardiovascular health, we’ll also review the cardiovascular system. So let me jump right in.
So the talk today is again on beet root and cardiovascular health. Let me go right into it. So those of you who are interested in understanding more about the range of things that I’m involved in, you can go to V A shiva.com, which is right here, which is a website and we’ll come back to this, but you’ll get a deep understanding that it’s really
Dr.SHIVA Ayyadurai 02:24
interesting that my journey to all of this has been integrating many, many different things be be it looking at science, engineering, innovation, running for office, etc. But the core thing about all of this is taking what I call a systems approach. So I’m personally very, very dedicated to educating all of you on a systems approach. So let’s get right into this.
Arizona here. Good to have you, Bonnie. So today’s talk is about beet root and cardiovascular health. So first of all, what is beet root? Well, it’s a root vegetable. And it was first domesticated first, in Middle East and native to Europe, and belongs to the amaranth, asay family.
Ancient Romans and Greeks use beets as an aphrodisiac. medicinal uses dates back all the way to Hippocrates. As many of you probably know, Hippocrates was the father of medicine. And Hippocrates believed that an individual who wasn’t their own doctor was a fool.
So one of the things we’ll talk about that when I go to give a little bit of a short discussion on your body, your system, I will also give you tools on how you can understand your body is a system. But the medicinal properties of beet root are our attribute it to the leaves, as you’re seeing here, the leaves over here, you can buy this obviously, in stores, and but then there’s also the root.
Okay, so it’s both pieces. What we’re going to learn today is the effects of beet root on biological functions to health benefits, we’re going to also understand the cardiovascular system, you’re going to get a review of that. And we’re going to look at how beet root affects cardiovascular health. And then we’re going to look at the clinical evidence on how much of beet roots you should take.
At a high level, you’ll notice that it’s a pretty well researched, you know, food, there’s over 8000 research articles that were done on it, nearly 283 clinical trials. Remember clinical trial is when they actually bring in human beings. And they tested on humans, not animals.
And they typically take a control group and a group that gets, in this case, a certain amount of beats, and a look at some functional difference. And there’s over 72 years of scientific research on beats. As you know, the approach that I take here is to use a technology that I created for my PhD work called cytosol.
And what cytosol have is it allows us in a objective way, and to look at what’s out there on the research. So here we’re looking at beet roots and cardiovascular health. And our goal is to find all the research that’s done in that space. Get that research, curate it, which means organize it.
And then go through that literature finding the molecular mechanisms, finding how beats the ingredients and beats. Remember, beat is a food product. And foods are really made up of many, many different types of constituent of compounds.
So when we say beet roots from a molecular systems level, we’re looking at the particular compounds on beats, that the research has found, has effects on cardiovascular health. And then we tie that together. And that’s what cytosol allows us to do.
But this is really the process we take, we take the papers, we curate the papers, we understand the molecular pathways, we get an overall architectural view. And then we do the analysis, okay. To those of you who are very, very excited about cytosol, and want to know more about it CytoSolve really emerged out of my interest to first understand the failings of big pharmaceutical enterprises, the way a pharmaceutical company actually works is when they want to build a drug.
And a drug is not something that occurs in nature. It’s a pharmaceutical compound that only is manufactured in a lab, right. And it’s typically a single comprehensive for pharmaceutical company to create something that’s called a drug that goes out to be sold, they spent about six years in what’s called Test Tube research, also known as in vitro.
So they’ll test that particular pharmaceutical drug in a test tube, then they’ll move it over to in vivo, which isn’t an animal, and that takes around six to seven years. If they make it out of that, then they’ll move to clinical trials, small sets of humans, medium sets, large, larger sets up to let’s say, 10 20,000 100,000 people, that’s phase one, phase two, and phase three.
Okay. So this is a pharmaceutical process. And what you notice here is most of the drugs that come out of this process only worked for 10% of the people, they have lots of side effects. And pharmaceutical companies, if you look at their top line revenues have been tanking over the last many years, which a lot of people don’t talk about, even though they spend more and more on r&d, which is at saffron line, less and less new drugs are in being approved by the FDA as I’ve shared before, because the FDA is recognizing that these products have side effects.
Now in the area of the job beings or the job a nation in that area, you can get a product out to market quote unquote, Operation warp speed with very little testing. And vaccines are actually growing. That’s why Big Pharma is moving into the bean factory. Okay. So that’s the background. So I created cytosol for my PhD work, because I felt it was going on was that the big pharma companies were doing this very
Dr.SHIVA Ayyadurai 07:40
medieval method, they’re coming up with stuff that hurts a lot of people has a lot of side effects. And the front part of that process is where all the problems were so I thought they would really like to use cytosol because our technology mathematically models a molecular pathways on the computer and gives a way to understand what’s going on without killing animals.
As we know, Fauci likes to beat up and kill animals. If you remember what he did with these beagles, he funded research to have I think beagles was their heads eaten off, right, John? Yeah, yeah. So by parasites, okay. So one of the goals of cytosol was to create a way that we could literally save animals without the need for animal testing.
So I want to share with you, for those of you who haven’t seen what cytosol is about, what is situs off so you get an understanding of that. So I’m going to play a quick video that’ll give you a deep understanding of what side of it so let me play this for you. Bring this up here. John, you want to bring it over here? Yeah, so for the Instagram people, we’re going to bring it over here.
So we could share with Instagram people what site to solve is so they also get an understanding of cytosol so videos for one second I’m bringing this up Okay, so here we go. So we’re gonna play a quick video on what is site assault so here we go.
Dr.SHIVA Ayyadurai 09:23
Who would have ever thought someone like me would invent email and create cytosol to revolutionize health for personalized and precision medicine a system for delivering the right medicine for the right person at the right time, I was born a low caste untouchable in India’s caste system, a system of aristocracy oppression and racism.
As a child I observed my grandmother, a poor village farmer practice Siddha India’s oldest system of medicine to heal local villagers by observing their face to know their unique constitution to deliver a unique combination of foods healing herbs and massage the caste system and her abilities to heal inspired me to understand the interconnectedness of all life.
My name is Dr. Shiva IRA. I’m an MIT PhD, a Fulbright scholar, a scientists, technologists and inventor my family and I left India to come to America on my seventh birthday. As a 14 year old I began working as a full time research fellow at Rutgers medical school to unravel the mysteries of sudden infant death syndrome SIDS and created the world’s first email system long before I ever heard of MIT.
As I traverse academia. Over the next three decades, I observed self serving academics never solving real problems writing grant after grant competing for tenure, while diminishing real science and real scientists pushing a reductionist science did destroy the scientific method like the blind men who never saw the whole elephant but the parts they delivered a dismembered view of reality.
I observed Big Pharma use such reductionism, wasting billions year after year to fund research and test tubes killing animals and using the poor as guinea pigs for clinical testing to create products that even the FDA no longer allowed not only big pharma practices reductionism, but also the elites of big vitamin B green and big new age with gurus and Yogi’s and powered by Hollywood celebrities selling one supplement after another based on a cherry pick science
All that changed in 2003 when the Human Genome Project ended, revealing that humans have the same number of genes about 20,000 as out of a worm giving rise to a systems biology we realize that one size fits all medicine was a failure we realized their medicines were killing us making today’s generations lifespan shorter than any previous generation obesity, heart disease deaths from adverse reaction to drugs, confusion on what diet what supplements and who to believe is what they have delivered you.
They push natural and organic products for your beauty and wellness. While their real solution is their plastic surgeons and Botox we’ve been sold out it’s time for real science AI systems science that interconnects the parts to discover truth to know what really works to get the health we need and deserve.
This is why I created cytosol cytosol was about truth, freedom and health versus power, profit and control. cytosol was a revolutionary technology integrating bioinformatics computational biology, mathematical modeling decentralization to reveal the truth cytosol computes trillions of potential combinations of biomolecular interactions to discover what actually works based on the actual science no reductionism, no cherry picking.
CytoSolve is predictive modeling has been proven accurate time and time again matching laboratory results. cytosol discovers synergistic combinations of compounds to maximize health and reduce toxicity.
For example, we know curcumin from turmeric and resveratrol from red grapes alleviate inflammation, but how much should we combine current methods are handwaving at best here with CytoSolve we first model the control condition with no curcumin and no resveratrol to simulate high inflammation with the cytokine level at point one, five micromolar Next we add just five micromoles of curcumin, the inflammation drops to point o five.
Next we use five micromolar as a resveratrol and the inflammation drops from point one five 2.06. But when we combine curcumin and resveratrol have three micro molars of curcumin and to micromolar as a respiratory inflammation drops from point one five 2.03 far lower, nearly 200% less than just one compound alone. That’s the synergy principle of system science.
We’ve all had enough of their fake and reductionist science, they think we’ll simply keep buying their marketing their celebrities and their products that can never truly heal us. We don’t need them great things come when we integrate the best of things.
It’s our time It’s time we delivered solutions for ourselves. It’s time for truth, freedom and health. It’s time for cytosol welcome. Alright, so that gives you a background on cytosol. society itself is really powerful technology that helps us
Dr.SHIVA Ayyadurai 13:40
really understand at the molecular systems level, what’s going on. So we can get out of sort of just believing in one person or the other. And especially in the world of vitamins, there’s so much stuff people put into this stuff.
And it’s all based on marketing, it’s hard to know what actually works. So one of the things that I’ve been doing for the last, particularly the 10 years is lot of the more evidence base, vitamin companies came to us and they said, Dr. Shiva, can we use cider soft to understand how the combination of ingredients work?
So we were doing that for probably the last 10 years. But over the last two years, what ended up happening was we found out that there were some we not, we had not we found out but we had discovered and created a whole bunch of mathematical models across many many different biomolecular areas.
So we started saying why don’t we use that to actually go end to end which means not only do it for other manufacturers, what about if we actually started creating and identifying products that actually worked for everyday people from natural products?
So that’s what ended up happening. And just as some of you have asked, you may know I have this bottle here that I never thought I actually learned how to do manufacturing of vitamins but this product of envy 25 That was created, I’ll talk a little bit about it really comes from applying the synergy principle.
So what we did here was, and if you want to go, you can go onto the shop site, and you can find it. But what we’ve taken is a systems approach. And this is something I want to point out, we can take a systems approach to understand the body. There’s a science called systems, system science.
But we can take that same approach, not only to understand your own body or my body, but you can look at the body of the organism of a political system, or your computer system, there’s a same science.
So using that same scientific approach, when we created MV 25, we literally looked at all the as as a back of the bottle says we looked at, as it says Dr.Shiva Mv 25 was formulated using the site of soft computational systems biology platform, a technology for precision and personalized health, invented by Dr. Shiva during this doctoral research at MIT.
This formulation results from integrating 1000s of peer reviewed scientific papers across four decades in 60 research institutions, and computing trillions of potential combination biomolecular interactions, to discover an optimal synergy of compounds that downregulated biomarkers of discomfort and swelling.
And one of the things here is, look, the reality is the formulation that we have here today could literally change because new science comes out. And the problem with the way that products are created is everyone thinks science stands still it doesn’t. Science keeps changing.
So as the science gets better, we’re going to actually find out other ingredients are put in there. But what we found was we found two very powerful bioflavonoids. And the right dosages, when you combine, they have a very, very powerful effect on pain and discomfort.
Obviously, everyone should consult your doctors, this is not a medical show. But the cool thing is, we’ve used this very powerful technology to figure out the right combinations. And we’re doing this across many, many other areas. And think about what we could do even in the area of antivirals.
We’re doing a project right now to look at every botanical in the world and find out combinations which have effects on supporting immunity, you know, fighting viruses, etc, independent of quote unquote, vaccines or to beans. Okay, so that’s just a quick side note.
So please go check it out. It’s certified clean, which means it’s non GMO organic made in the US. And you can go right to the VA Shiva site, you can shop there, and on the shop over here, you’ll see MV 25. And please go take advantage of it. Thank you.
So getting back to beetroot, what we find is, so we want to take the same systems approach to understanding beets. What is beets? Well, beets are a root vegetable that occurs in nature. But more importantly, from a system standpoint standpoint, beets fundamentally are composed of many, many different kinds of compounds, right? They have minerals, vitamins, poly phenols.
So when you want to think about any food you’re eating, the food itself is its own ecosystem. So when you take that food into you, your ecosystem is interacting with that food. And that interaction is a result of the beat route as a as a as a unit, but also based on the kinds of things that composes a beet root. So what what what, what are beet roots made up of?
Well, beet roots are made up of fiber, proteins and fat. These are called macro nutrients. So when people say hey, what do you mean by macronutrients? You mean fiber proteins and fat right? And the macronutrients in this case if you take about a couple of beats, right?
Three 3.4 grams is fiber. 2.2 grams is proteins. And point two grams are fat. So there’s still fat in there. micronutrients are other things right there, the vitamins, the carotenoids, the thing that give it the color, the beta lanes, the minerals, phenolic compounds, and inorganic nitrate. We’ll come back to this because this is one of the powerful effects. White beets have an effect on cardiovascular health, the nitrates in it and we’ll come to that, okay.
Dr.SHIVA Ayyadurai 19:15
All right. So, the vitamins, what are the vitamins and beets? Why is he noticed there’s a whole host of B vitamins, vitamin K, vitamin D, vitamin E, from B, one, B, three, B, five, b, six, B nine, and B 12. And beets also have a ton of minerals. Remember, it’s a root vegetable root vegetables are in the ground, they’re getting a whole range of minerals.
As you can see, 100 grams of beets have potassium, phosphorus, calcium and magnesium. And there’s been a lot of debate in the vitamin world on how much calcium and magnesium should should you take. Some people have said you should take two to one, which means for every one part or two parts calcium should take one part magnesium, other people say said it should be equal.
If you notice you’re counting Even magnesium occurred nearly in the same levels of magnesium being a little bit higher. And you’ll understand that magnesium is extremely important for many, many different functions because magnesium, it calms the system.
Okay. But the other thing we’re going to cover is beats have a whole range of phenolic compounds apigenin in fact, apigenin is one of the ingredients we’ve put in MV 25. Okay, it’s one of the very powerful bioflavonoids and you can go research apigenin, but it’s in MB 25.
It’s got beta garden, beta, Vol. Garren, caffeic acid, chlorogenic acid, and ferulic acid. Okay, so these are the phenolic compounds, and you can see what they look like here. So you can see here’s beta ln, here’s apigenin. Here’s beta, Garenne nitrate and beta valguero.
And these are the active components in beetroot. So this is the ones that we’re going to focus on, really, for today’s discussion, because these are the things that the research says not to say, again, science may find out their other active components.
But what I’m sharing with you today, this is based on what’s in the scientific literature as of today, okay? So if you want to talk to your friends, you have medical doctors, you can point them to the research, and all of this is coming from existing peer reviewed research.
Okay. So what are the biological effects of beet root? Well, first of all, beet roots have all of these six very powerful biological effects, anti inflammatory, antioxidant, antimicrobial, anti hyper, lipid Demmick, which means they burn up fat, anti hypertensive, and immunomodulator, which means they modulate the immune system. It’s like giving shock absorbers your immune system.
What are the health benefits? Well, health benefits of beet roots are the following First of all, relative to cardiovascular disease, which is what we’re going to talk about today is hypertension, arterial sclerosis and heart failure. So beats roots have a very beneficial effect on these diseases, but they also support diabetics, people, liver conditions, Upad, otitis and infections.
Okay. Now, what I want to do is, I want to take a little bit of time, I’ve done this before, but we want to take a systems approach. So now we understand what beats have lots of minerals, vitamins, phenolic compounds, we’ve gone over their key active ingredients.
But what we want to talk about is, that’s the system here beats and then within your body is something called a cardiovascular system. So how do beats interact with your cardiovascular system, in order to understand that we need to understand what the cardiovascular system is.
And that word system is extremely important, because you have various you your body is a system, you have the cardiovascular system, you have your digestive system, you have your, you know, your, your nervous system, these are all systems. So the question is, what is the system, and one of the things that I’m committed to educating all of you.
And in fact, ensuring that all of you get better educated on all of this is really to understand what is a system. Okay, so I want to take a little bit of a quick definition of that, to let you know that in order to support you in this education, because if we, if you don’t learn system science, if you don’t learn how these things are interconnected, you’re always going to be relying, and you’re always going to be second guessing yourself.
So there’s a science of systems. So I spent a lot of time putting together a methodology, so you could understand the science of systems. So I want to share with you a couple of things here. So if you if everyone, we put this up here, if everyone has a chance, go to a put the little ticker here, go to truth, freedom health.com.
Because the truth, freedom, health calm, what you will learn is the science of systems, I’m going to share with you my screen here. So if we go here, one of the things we’ll learn is make it back here.
Dr.SHIVA Ayyadurai 24:07
I want to share with you here that if you go to truth, freedom, health, calm, that’s this website. And I want all of you to go there, because I’ve created a way that anyone, whatever your educational background is, you don’t have to be an MIT guy. You don’t have to know math.
But if you go to truth, freedom, health calm, it’ll take you to this site right here. And the truth, freedom, health calm, you can go down you can support yourself because we’ve created a movement here called you can become a truth freedom and health warrior.
What I’ve done is I want to give all of you 15 different gifts. Let me explain what those gifts are one of the gifts is the gift of Hey, John, can you bring the camera here? One of the gifts is you get the gift of we have a whole range of other videos which are premium videos.
When you sign up, you get access to the truth freedom and health warrior videos. The second gift is there’s a very founding national paper that I wrote, which will teach you the integration of eastern and western medicine, and that’s the call the Rosetta Stone, the next thing is you can actually take the science of systems course, you can actually get certified.
And you can see this is an immense value for many, many people that we used to sell at a ridiculous price, and people were paying for it. But this was for people at a lot of money. And I wanted to make this accessible to more people. That’s called the science of systems course.
The next piece is there’s a book called system and revolution, which all of you get, you also get access to three other books, where you can apply the science of systems, your body is a system, how you can use systems to understand politics, etc. The next piece here is you can also there’s a tool, which you’re going to be discussing tonight, call your body, your system, your body, your system is a tool that will literally give you an understanding how your body is a system.
In fact, if you go to this website, if you want to know more that I’m sharing my screen, I might Yeah. So if you go to your body, your system, you’ll you’ll see, this took me about 20 years to create. But there’s a tool that you can really answer set of questions, figure out what kind of system you are, that red dot represents your system in this triangle, then you can answer a different set of questions.
And we’ll figure out how your body is off course, you didn’t get enough sleep, you were eating the wrong things for you. Okay, everyone is different. And then you can figure out a foods and exercise and activities will bring you back to you. So that’s the your body your system tool.
The other thing we also give as a part of this capabilities, I want to give you guys, his scientific reports on different types of herbs, you will also get access to an entire forum where you can meet other truth freedom and health warrior scholars all over the world.
And then you can also do get access to a social media site we’ve created for people independent of big tech. And then obviously, we’ve created activism tools, and I’ll come back to this. Okay. But I wanted to share that with you.
Because what I meant when I talked about the cardiovascular system, the cardiovascular system is not just made up of one thing. It’s made up of an organization of many, many different things. So John, I guess we can you want to leave it here, John, because if it’s pointed at this, I think people can also see this right? That’s okay. Yeah. Right. I think that’s good.
So let me go back to our PowerPoint, and share the screen here. So let’s go back to this. So we’ll come back to truth, freedom and health before and I’ll walk through more of this. But if you look at the cardiovascular system, and can everyone on Instagram, see the whole thing, John?
Yes. Okay. If you go back to the cardiovascular system, one of the things we’ll understand here is that the cardiovascular system is composed of multiple units. And when you take the course you’ll actually understand what is a system but you notice a cardiovascular system is composed of the heart, which is a pump blood vessels, which are the things that deliver the third item called Blood. So what’s the heart? Well, it’s
Dr.SHIVA Ayyadurai 28:00
a powerful muscle responsible for pumping blood throughout the body. What are blood vessels were they’re the things that carry the blood and nutrients to all parts of your body. And then what is blood composed of? Well, blood is composed of blood cells, red blood cells, things like that plasma, which has, you know, a whole range of nutrients.
And the red blood cells carry oxygen, the plasma has a white blood cells, which provide immune support. Okay, so when you’re when your heart and your circulatory system or cardiovascular systems working well, not only pumping blood, but you’re also supporting your immune system, right? So exercise is very, very important for the immune system.
So let’s look at the blood vessels, okay. And that’s called the vascular system. Okay, it’s composed of three kinds of blood vessels, arteries and veins, and then capillaries, which are the fine vessels, but the arteries are the things that carry oxygen to the cells.
Okay, so arteries are carrying oxygen from your, so if you look at here, here’s your lungs, and your lungs are oxygenating the blood and that goes up to your left atrium. So the left if you’re touch the left side of your heart, that’s your left atrium, and then your left atrium, it pumps stuff through your right atrium, through the rest of your body.
And then your, your right atrium, okay, which is on the right side is receiving the deoxygenated blood, and that thing gets sent to the lungs to get oxygen and that’s your cycle. Okay, so these the arteries are the ones that are carrying the oxygenated blood all through your Capra capillaries, right, so the arteries are the large blood vessels that carry oxygenated blood away from your heart, and the veins are the ones that are carrying deoxygenated blood to your heart and the capillaries stand in between.
They’re the small vessels that deliver nutrients and oxygen to the tissue and they’re also removing the waste right? So if you look closer at this, the arteries Have these three components the Add Ventus? Yeah, the tunica media and the tunic. Intimate, okay. And so the tunic intimacy, inner layer. The adventure is the thick outer layer, okay? It’s the thing that provides shape and the and the tunica
Dr.SHIVA Ayyadurai 30:18
media, okay? I’m sorry, the tunica media is a middle layer and the tunica intimate is a is a stuff. That’s the surface of these vessels. Okay. Hey, John, I’m about to run out of juice, can you neither juice thanks. And so what you see here is, so the arteries and the veins have similar systems here, right? Um, the, the thin walls are relatively thick, you know, tunic adventure in the veins here, and you have thick tunica media here.
So the differences in the arteries, you have more thicker tunica media, okay, which is a middle layer. But in the veins, you have thin walls, and you have a relatively thick Tunica adventure, okay, which is the outer light, right? So the outer layer is more thicker relative to the arteries. But when you go to the capillaries of capillaries are really composed of what are called endothelial cells.
And that’s really just a Tunica intimate, which is the inner part. Okay? Now, when we look at the cardiovascular system, one of the important things we have to learn is a role and to really understand when you’re making decisions on what foods you should eat, what’s supported for you. One of the key biomarkers is something called nitric oxide.
Okay, nitric oxide, I think about 10 or 15 years ago is a big article in Time Magazine saying it’s really the molecule of the century, because nitric oxide is the thing that supports vasodilation. It was the basis of the discovery of the of the drug called biogro. Right, but what is nitric oxide?
So nitric oxide is a potent basal dilator. Okay, is a key role in maintaining blood pressure. It’s anti our thermogenic against you know, arthrosclerosis it’s generated by e nos catalase. Okay, well, we’ll talk about this. Okay. And Enos catalase. I’m sorry, it’s generated by Enos, which is a enzymes catalysis of L arginine. So you get nitric oxide when l Arginine is, is catalyzed.
And that’s when you get nitric oxide. And when you exercise I want to talk a little bit about when you exercise, what’s really amazing is when you exercise, you have blood flow that starts moving through your artery through your veins, and through your capillaries. And that blood flow helps to release nitric oxide. So that’s why exercise is good. And that’s through a process called shear stress.
So let’s look at that. So what is shear stress? Shear stress is the following. So here’s your capillary, let’s say the surface of the copper is composed of these hexagonal things are called endothelial. So when you exercise, you get blood flow. And so the flow of the blood is not perpendicular. It’s shear, right? It’s parallel to the endothelial.
And so when blood flows like this, it causes a production of nitric oxide. And how does that happen? endothelial nitric oxide synthase, E and O S. Right? So it’s a, it’s a enzyme that converts l arginine. So you have to have arginine. So what that means is a diet needs to be composed of some good levels of arginine. So in the presence of arginine, what happens is that that
Dr.SHIVA Ayyadurai 33:34
enzyme converts arginine to no to nitric oxide and also L citrulline. And no production leads to vasodilation. Right? And the maintenance of blood pressure, right? That’s what happens. This was the basis of creating Viagra, okay? You’ve a so dilate, you get more blood flow.
But that’s what no production leads to. So I want to share with you the work that I did when I was at MIT with Harvard and brigands and King’s College on No, so one of our key researchers, Andrew Kuhn, in our lab, had figured out how to send flow shear flow, and he could measure nitric oxide release.
But as Andrew started looking at the endothelial he found out here’s the end. So you’re looking at one cell on the surface of the endothelial and what you notice is that the endothelial has various molecular reactions taking place, but on the surface of the cell, is this interesting structure molecular structure called the glyco calyx, Okay, looks like a Christmas tree.
So, in blood flows over this Christmas tree structure starts shaking on the outer surface, and on the inner surface, it leads to a whole series of chemical reactions. That so the mechanical change mechanical force on the glycocalyx, which is from let’s say, you’re exercising running, your blood is moving that leads to the conversion of L arginine via nitric oxide, you know by the enzyme to it.
Nitric oxide by the enzyme Enos, okay, that’s what occurs. Now if you go read the literature, you’ll find all these different. So if you wanted to do this on your own to figure out what’s going on, you’ll find hundreds of papers, talking about how nitric oxide gets released through this process of chemical reactions, and there’s many, many, many, many kinds of chemical reactions that are involved in nitric oxide.
So if you wanted to get a holistic view, it becomes very complicated. But with cytosol, what we were able to do was take all what’s in the literature, bring them together, and have cytosol, convert those ball and stick diagrams, all that literature into mathematical equations, which were then able to compute how much so the x axis is time, the y axis is the amount of Enos, which is that enzymes mRNA concentration that’s released.
So this is a mathematical prediction. Again, without killing animals, cytosol was able to predict how much nitric oxides are agnostic, the enzyme is released, right? Or the amount of mRNA for that enzyme, which produces that enzyme. So the issue is people always wondered, well, that’s a mathematical prediction doesn’t match reality. And lo and behold, it does.
So this was Andrews work looking at the actual in vitro, and here we’re getting the exact same results. So shows that cytosol is able to predict what’s going up in the test tube. And same here, we’re looking at the protein. And same here.
So this is quite extraordinary, because what we were able to do was to show that we could model the cardiovascular system for in terms of nitric oxide release, and then match those to the actual wet lab results. Okay, so you can save a lot of time and money.
And this is published, by the way in one of the leading journals, I was one of the authors along with a great team of people. So when we look at the effect of beet root on the cardiovascular system, we know that beet root from the literature is known to have hypertensive effect, which means lowers hypertension, anti diabetic, very, very beneficial for diabetics, and also our throat, you know, from stopping arteriosclerosis.
Okay, so how does this work? So now let’s so now that we understand what’s in beats, we understand what is a cardiovascular system? How do we put this together to understand what is the value of the roots to you. So in order to do that, what we’ve done here is, we want to look at the anti hypertensive effect. So that means to lower hypertension. So it turns out is remember, your when you the beet roots have nitrates in them, that’s one of the important active ingredients.
So when you eat beet roots, your mouth bacteria, again, this is why the mouth microbiome so important, we’ve talked about this. So if you have proper mouth health, right, take care of your teeth, and you have the oral bacteria in your mouth interact with the nitrate, and it’s converted to nitrate, when this nitrite decomposes to nitric oxide right here. Okay? What happens is, is nitric oxide enzyme activates enzyme soluble guanylyl cyclase SGC. So you eat beets, you chew on them, right.
Dr.SHIVA Ayyadurai 38:16
And then you get nitrites, you get nitric oxide. This is why a lot of people drink lots of these juices, you know, and I’m a big proponent, if you’re going to drink these concentrated vegetable juices, etc. My view is you should let them at least be in your mouth for a little bit. So your oral bacteria and your mouth enzymes can react with it, because it’s part of the digestive process.
So here, you see that the nitric oxide gets created, which then gets activates this enzyme called S G c, soluble guanylyl cyclase SGC. And then SGC is able to convert GTP to cGMP. So what is cGMP? This is a very important, a very important chemical in, in, in smooth muscle cells, right? And it’s important to leading to the relaxation of the blood vessels in those smooth muscle cells.
So cGMP relaxes us that’s called basal relaxation, which promotes anti pretension effect in the blood vessels. So blood is able to go in Okay, so there you go. So that’s, again, from beets, we’re looking at one of those chemicals called the nitrates. When you digest them in with your oral bacteria in your mouth, you get this effect of producing a very powerful set of reactions, which promote an anti hypertensive effect. So that’s one of the chemical processes they’re anti diabetic effect.
Okay. Remember I talked about well, in MV 25. Some of you joining knew I talked about the product that we created from cytosol it has one of the ingredients is apigenin the others has ferritin. But we figured out the right combinations have the most powerful effect in this case for a pain and discomfort, but here apigenin apigenin from beet root and the beta ln also from beet root, these are two very important active ingredients.
Look what they do to have anti diabetic effect. First of all endothelial dysfunction, which is the cells in your, you know, in the vessels in the heart is caused by oxidative stress. So, if you if your heart is not functioning right or you have and this leads to diabetes, when you have endothelial dysfunction, you have basically the, the oxidative stress caused by superoxide and hydrogen peroxide. These are two very powerful oxidative chemicals, right?
You don’t really want these in your body, a lot of it okay. superoxide and hydrogen peroxide, they lead to endothelial dysfunction, okay, right here. Now what happens is that BT Alain from beetroot and apigenin through a series of reactions, they upregulate this chemical called NRF, two, so NRF two, there’s a lot of research being understood about NRF two and it’s valuable, valuable effects for your body. So what is NRF? Two do okay?
So NRF two, as you can see here, leads to the formation, okay. And it promotes the anti oxidize enzymes, superoxide dismutase and catalase. These are two very powerful enzymes, which break down okay, which stop I’m sorry, stopped superoxide and hydrogen peroxide. So again, these two chemicals are oxidative chemicals are the oxidation is like rusting.
Okay, leave your bike out outside and starts rusting. So if you want to think about these two chemicals, as we’re talking about here, superoxide and hydrogen peroxide, they’re like the things that cause your quote unquote, your endothelial dysfunction or rusting, but superoxide dismutase SLG as well as catalase stop that, stop that oxidative effects. These are two very powerful antioxidant, antioxidant antioxidant enzymes.
The other thing is beetling itself also eats up a lot of superoxide it also comes here and from here. So this basically neutralizes oxidative stress, which stops endothelial dysfunction, ensuring that it has an anti diabetic effect. Next thing is you can also see the anti diabetic effect comes from the carotenoids the rich thing things in beats that give it all their color, the carotenoids and the Badaling. What do they do, okay,
Dr.SHIVA Ayyadurai 42:59
they have an effect on you know, lowering cholesterol, okay, the bad cholesterol, LDL. So that’s low density lipoproteins, that’s known as a bad cholesterol. And this gets oxidized to become Oh x LDL right here. So LDL becomes Oh x LDL. And that is what causes plaque formation, leading to arterial sclerosis. I’m sorry, this slide. We just go back to this. I just want to edit this slide.
This is anti arterial sclerosis art, or serial. Euro sclerosis. Okay, sorry about that. Go back to this. I wanted to just fix that slide for everyone. There was an error I made in that slide. Let’s go back to the sorry about that. So there we go. Okay. So anti our thorough or Theriault sclerosis Okay, have an extra Ian here, it’s okay.
But so when you get arteriosclerosis LDL, which is a quote unquote bad cholesterol is going to Oh x LDL, forming plaque. Well guess what happens superoxide Okay, leads support so superoxide is the thing that enables the LDL to gold go to the O X, LDL sone of endothelial dysfunction this happens and guess what happens BT Elaine and carotenoids block this reaction.
Okay, so we’re talking about his LDL goes to Oh x LDL, which leads to plaque formation, and the beet roots stops that formation. Okay. So that’s the advantage right there. Okay. It stops that formation. So in closing, you can see the powerful effects of these products.
What I also want to do is if you take a systems approach, Dennis shield Good point. Dennis also says you want your body to be alkaline. That’s right. alkalinity. Nidhi also have its very powerful effects. Matt Blackburn says that and glutathione peroxidase is another Power NRF two enzymes.
Thank you, Matt for sharing that. Okay. And Susie says that juice, organic beats roots and all makes a great smoothie with fresh organic mangoes. That sounds good. Um, so going back to our slides here, the other way that I want to teach you to look at beats is from a systems approach, okay?
And in the systems approach, there’s a, as you know, what I’m gonna do, I’m gonna play for you, the, I’m gonna come back to your body, your system. I’m just gonna take a quick break here, because I want you guys to understand that we want to take a systems approach.
And the research that I did for my Fulbright work where I integrated Eastern medicine, found the linkage between Eastern medicine and Western engineering to some theory lead to a tool call your body or system. But the foundations of that science system science is what I teach every Mondays and I want all of you to become truth, freedom and health warriors.
So I’m going to take a quick break and share that with all of you. So it’s right here. So let me stop the screen here. Let me share with you this video file, which will give you a little bit of understanding of what that movements about so here we go. Come back shortly. Hey, John. Oh, that’s already pointing here right. So we’ll see that so everyone listening this is
Dr.SHIVA Ayyadurai 46:24
Hello, this is Dr. Shiva IRA. Welcome to VA Shiva the platform of education, technology and activism so you may raise your consciousness to win the truth, freedom and health you need to create the future you deserve.
The VA Shiva platform provides this truth freedom health warrior scholars the following three capabilities number one and ultimate education that is based on the science of systems number two technologies to empower you to take charge of your health as well as social media tools independent of big tech so you can connect with other incredible truth freedom health warrior scholars equally dedicated like you to winning true freedom and health.
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The science of systems will enable you to uncover the real problem and real solution in any situation and on any issue concerning the educational component. First, you will receive direct access to me to learn the science of systems in my three hour lie private online group class that I run every week.
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Finally, to support your education. I’ve also included a seminal scientific paper that I wrote, which will help you understand that the knowledge of systems it does not only originate in the modern world starting in the 1920s, and 30s, but it actually dates back 10 to 20,000 years and intersects directly with the foundations of Eastern systems of medicine.
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Dr.SHIVA Ayyadurai 50:45
Right, so that should give you an understanding. So if you want to know more and become a truth, Freedom help where you go to truth, freedom, health calm. But one of the analysis that I wanted to show you’re using the systems approach, you can also now get a deep understanding of how to look at beats from a systems approach.
If you go to your body, your system, you’ll understand that there’s a capability that’s been created. So you can actually understand another way to look at your bodies as a system, your body has the forces of transport, forces of conversion and storage.
Again, I don’t have time today to go through all the details, but everything in the universe, including your body runs on these three forces. So you can understand how those forces are present in your body, when you understand when you use a tool, your body, your system, and then how your body’s off course, which is a black dot here, right the red.is where your target is, every one is a unique system.
And then the issue is health is allowing your body to function and in this model, and its homeostasis from a system standpoint. So if you can bring the black.to the red dot, and that’s what foods and different things can perturb you or activities and bring you back.
So those of you who do not want to become a warrior but you want to just become a supporter go get the product you have access to it and the book and it’s a very very small contribution that gives you access to that.
So when we look at beats, beats if your body is here, liquid beats two beats actually stabilize, move transport right some things can make increase like coffee increases the aspect of transport or certain foods may aggravate conversion which is your digestive process but BT stabilized both of these but they actually increase Kapha storage which means they support you know bones and tissue right?
Which are important for your building blocks for for you. So beats have a very powerful effect on building your structural components. So a bunch of have been asking how much do you take Okay, well, if you want to look at the components if you look at the Baden in from beetroot extracts for coronary disease, according to research done recently 2020 biketour all but 100 milligrams per kilogram extract per day.
There there are supplements you can get Baden in supplement for glucose control again, what I’m giving you here so you have beats and then you have the active ingredient which you can actually get as a supplement Excuse me.
So Baden and supplement for glucose control. Hon at all in 2015 said you need about 100 milligrams per kilogram of extract per day. For hypertension, beetroot juice Number Have you been chatting you’re seeing you take beetroot juice, so it’s very, very valuable for hypertension 250 milliliters per day. So that’s a quarter of a leader, okay, quarter of a leader that just came out recently 2019. So in summary, beet roots have several benefits for cardiovascular health, right?
One is a nitrate from the beet root releases basal dilator nitric oxide, which lowers hypertension. And we talked about that the beet root also provides upregulation of antioxidant enzymes that mitigate diabetes via downregulation endothelial dysfunction caused by oxidative stress. So basically, in layman’s terms, there are chemicals in your body hydrogen peroxide.
So you know superoxide, which are highly highly quote unquote rusting oxidative chemicals. And what beet roots do is they actually turn on antioxidants, which which inhibit that. And then the other thing is when it comes to arterial sclerosis, which is plaque hardening of the arteries, beet root compounds prevent that by down regulating oxidative stress. And that that which is the thing that’s involved in causing plaque formation and hardening of the arteries.
So, when you really think about beats, what we’ve just done here is we’ve we’ve looked at beat route and cardiovascular health from a systems approach. So I want to encourage all of you to go back Look at the video as many times as you want. Tomorrow, I’m going to be doing a video on spinach, and cardiovascular health, but that’s our cardiovascular series.
But the thing to really understand is that you’re looking at systems, food is a system, your body’s a system. And when we take a systems approach, as we say, goes beyond left or right, okay, that’s when we start looking at problems in the world.
We want to take, we want to, we want to take a systems approach, the same approach we’re taking to understand the inner interactions and connections of things, to understand how beats may or may not affect your cardiovascular system. That’s the same thing we can look at, hey, will this policy deliver us more truth, freedom and health? And what will this do to affect election integrity? What
Dr.SHIVA Ayyadurai 55:43
will this do to affect censorship or freedom? It’s a systems approach. And without that systems approach, it’s very, very easy to get drawn to the left or the right. So I hope this is valuable. Let me see if there’s any other questions. Thank you for all your positive comments.
But please, you know, study this video. There’s a lot of content here. I hope you enjoyed this. This evening, I’m going to be doing a whole lesson with one of my colleagues on your body, your system, but one of the very powerful ways you can support our research and support more importantly yourself is go become a truth Proven Health warrior scholar.
It’s a pretty nominal contribution compared to the value that you get, but you also support us to be able to do all this research to support your learning and growth. Thank you, everyone. Have a good evening. Be well Happy Friday. Thanks, John.
The original research in this video is made possible by generous contributions from supporters of the Dr.SHIVA Truth Freedom Health® movement. Please contribute so we may continue to bring you such original research, valuable education, and innovative solutions.
Dr.SHIVA Ayyadurai, MIT PhD in Biological Engineering, the Inventor of Email, Scientist, Engineer, Educator shares Beetroot and Cardiovascular Health. A CytoSolve Systems Analysis.
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