CytoSolve® reveals that MOLECULAR HYDROGEN affects 3 molecular pathways involved in IMMUNE HEALTH. Short video above. Full analysis: https://vashiva.com/dr-shiva-live-what-is-molecular-hydrogen-how-does-it-affect-the-immune-system/
Transcript Below.
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meaning everyone, it’s Dr. Shiva Ayyadurai. Today we’re gonna be talking about molecular hydrogen, what is it and how it affects the immune system.
And what’s interesting about molecular hydrogen is it’s been around, right? As you know, h2 is what if you remember from basic chemistry, it’s one of the most important elements on the periodic chart, if you remember from chemistry, but as a substance that we use actually to support our health. It’s something that’s relatively new. When we look at molecular hydrogen, what we want to look at here is first of all, what is it? What is molecular hydrogen, so if you remember your basic high school chemistry, if you remember this, you will find out that hydrogen, h2 Because hydrogen comes in a pair, because hydrogen has one electron, one proton, the other hydrogen has one electron, one proton, and they, if you remember, Chemistry, they want to fulfill two electrons.
So they come together, and it’s a smallest molecule in the universe. And it’s a stable gas. That’s what h2 is.
It’s a smallest molecule and stable gas and the effects of hydrogen, but now reported on 63 disease models and human diseases, and it exerts very powerful medicinal effect on through antioxidant and anti inflammatory properties. And what’s wonderful about this is that there’s little to no adverse effects. Compared to other antioxidants.
You have to be careful, even though everyone says just take all the pills you want, it’s actually not true. Some of these pills that you take, you have to be careful with, because if you don’t take them the right way, you can have problems at the biological level. But hydrogen, what’s interesting about it, it has very, very little known effects on adverse effects.
So that’s one important thing. The second thing is the delivery of the hydrogen molecule can be inhaled hydrogen, you can also get hydrogen rich drinking water. This way of hydrogen gases dissolved in the water, you know, just like you get bubbly water.
This is hydrogen gas and hydrogen producing tablet and waters you drop the tablet in and the hydrogen enriches us and the drip infusion of hydrogen rich saline. That’s another way or you can do direct diffusion of hydrogen through baths and eyedrops. So these are the four delivery mechanisms, you can either inhale it, you can get hydrogen rich drinking water, which is dissolved hydrogen gas and water, you can get drip infusion of hydrogen rich saline, which is saltwater, or you can do direct diffusion of hydrogen through baths, I wanted to let you know that we use the technology here.
We’ve helped many, many companies over the last 16 years, a lot of smart, innovative companies. But we decided with all the mathematical models we’ve created, why don’t we try to use this to compute the best product we could think of from the science out there for reducing pain and inflammation, pain and discomfort. And that resulted in us Creating m v 25.
Using cytosol. We’re going to have more products that are going to be coming but let me just show you what MB 25 is about for those of you who haven’t heard about it, but this is using psilocybin a beneficial way not to just do research, but fine combination therapies. I am firebrand, my hands would cramp up so that I couldn’t hold cards or knit or crochet.
And they would go like that. Not have to use this when I played cards with my grandkids and I started taking that and the 25 after betta was able to hold cards in my hand. Very, very little cramping hardly at all anymore.
MV 25 Hi, my name is Sandy. I’m a Taekwondo instructor, I tore my ACL during Taekwondo, I had a lot of pain and limited mobility. I’ve been taking the MV 25 for about six months now after the first week, I noticed the big difference after the second week, almost literally no pain.
My name is Jeremy and I suffered from a lower back problem hurt my back at work years ago. And I can go to the chiropractor and do all kinds of different things. And nothing seems to help.
And I decided to try MV 25, I didn’t notice a difference immediately. But within a few days of pain went away and it stayed away. I’ve continued to take it.
And even when I do things that I shouldn’t do, it seems to go away a lot quicker than I ever did before. It’s clean food certified, it’s made in the US if you go to Bac va.com Right on the shop, you’ll click there or you can go right to MB 25 dot life either way, and then from there, you can click on the bottle and you can order please take advantage of it because first of all is going to help you it’s going to help our movement and it really supports the fact that we want to take science based approaches to natural products.
So let’s look at all the different health benefits. It’s quite immense that the different health benefits first of all, inflammation, autoimmune disease, obesity, chemo dialysis for people with kidney issues, right cardiovascular disease, radiation effects, neurodegenerative disease, cancer, infections, and sepsis, metabolic diseases, type two skin disorders, neuro muscular diseases, ulcers and inflammation. So think about it in the universe.
This is a smallest molecule and so it’s clear that we live around hydrogen so it’s probably extremely valuable if you just use your intuition for our advancements. So just to summarize, hydrogen has many, many health benefits. What we’re going to do now is to really understand How those health benefits can affect the immune system.
So let’s go into looking at that a little bit deeper. So just a few months ago, this wonderful paper came out in nature, which is one of the most prestigious journals in the world. It said hydrogen rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults, a randomized, double blind control trial.
So before you know we were talking about this before we’ve done research on it. But whenever you talk about these kinds of alternative treatments, typically the medical community comes out says this is garbage. Well, this paper has come out in nature in Scientific Reports, by the way, there’s been 4600 papers written on hydrogen.
So what’s wonderful about this paper is they did a actual double blind control study, really looking at how it reduces inflammatory response. And so you can see they brought in about 158 patients here, they’re randomly assigned them, right? They about I think they excluded a bunch of people because they didn’t meet the inclusion criteria. So they had a total of 41 people 19 In that group who just got plain water, and then 22, who got the hydrogen rich water, and no one discontinued here, you have two people discontinue here.
So your total of 20 people at the end of the study, and here you had 18 People here. So you had eight, the same people started close to the same people started, one person withdrew here, for some personal reasons had 18 People here and 20. So it’s not a you know, it’s a pretty sizable group of people.
And this is what they found, they found that hydrogen rich water reduces inflammatory responses prevents apoptosis of peripheral blood cells in healthy adults, a randomized, double blind controlled trial. So this is quite extraordinary, because it reduces inflammatory responses. So it comes from an important study.
So now what we want to do is we want to understand the effects of hydrogen. This is what got us interested because we want to focus on the immune system. So what is the immune system? Well, the old model of the immune system according to Fauci, and unfortunately, medical doctors who don’t really get a full education, this is the only two boxes that they learned, they learned about the innate immune system, which is when a virus or pathogen or fungi parasite comes to you, this is all parts of your immune system in your gut, in your mouth, in your eyes, that’s where you have all these cells, like the Marines, which try to take it out.
And then based on how this works, you have the other box in this two compartment model called your adaptive immune system. This contains, by the way, cells, like macrophages and neutrophils, this contains different set of cells called T cells, and B cells, when people were getting AIDS, right, their T cell count goes low, so they’re not able to produce antibodies, the adaptive immune systems job is to recognize the antigen from here and create the appropriate antibody. This is a navy, like seal sharpshooter, these are the Marines would just go in and start shooting.
And this has been the old model of the immune system. But the reality is, this is not a complete model of the immune system. The truth is, this is a much more deeper understanding of the immune system.
And what you see is you don’t just have the innate and the adaptive, but you have the interferon system. Last week, I did a detailed talk on the interferon system. But we also have all the bacteria in our gut 60 trillion, the viruses around 380 trillion, we have our brain, all of these systems are interconnected.
And this is really the immune system, what we need to do if we really want to understand how things work, we need to take this systems approach. And part of this I just want to emphasize your systems approach really gives us the ability, one of the things is to understand synergy of things. And what do I mean by that synergy means it’s not any one component that affects us.
So if you just exercise if you just eat well, or if you just get enough sleep, you’re gonna get a certain performance of health. But when you do all those things together, that’s when you get incredible health or real health, anti aging type benefits, but that’s what the synergistic effect can do. So when we look at molecular hydrogen here, what you want to do is we’re looking at the synergistically what it’s going to do inside the whole body, not just by itself, when you look at molecular hydrogen, it modulating immune response by three ways, synergistically, it’s not it doesn’t just hit one thing.
That’s what’s cool about this, it’s not just doing one thing, it’s hitting multiple subsystems in your body. First, it’s reducing these pro inflammatory cytokines very similar to these cytokines I just shared so it reduces a cytokine storm in your body, it up regulates anti inflammatory enzymes, and the next thing it does it prevents aggregation of immune cells, which leads to inflammation. You don’t want the immune cells clumping together, that’s when you get more inflammation and molecular hydrogen prevents apoptosis of the innate immune cells, you don’t want your immune cells dying off such as macrophages, thereby improving the immune response against pathogens.
So apoptosis means cell death to big word, I mean cell death. All right, so let’s look at this. So first of all, let’s go one by one.
We’re going to look at the suppression of inflammatory cytokines and enzymes and molecular hydrogen what it does, it stops oxidative stress. And this is really good because that promotes the oxidative stress. By the way, if you look downstream, oxidative stress is bad because oxidative stress creates this very horrible molecule.
You don’t want this in your body can10:00Answer is very closely associated with this molecule called NF Kappa Beta and NF Kappa Beta is not good because look what it leads to these four very inflammatory cytokines, il six, TNF alpha, il 12, and il one beta. So if you want to act you want to share party you can say NF Kappa Beta regulates il six TNF alpha, il 12. And il one beta which leads to inflammation and NF Kappa Beta also leads to Cox two which leads to PG two which causes inflammation by the way, when you take Advil, Advil blocks Cox two it’s called a Cox two inhibitor.
So what we’re seeing here is this transcription of NF Kappa Beta. This promotes expression of Cox two as well as all of these inflammatory cytokines, which leads to inflammation. So what is molecular hydrogen do it blocks oxidative stress, which stops this domino effect.
The bottom line is that hydrogen molecular hydrogen stops oxidative stress, which stops NF Kappa Beta. So it’s a dominant once NF Kappa Beta falls, you get all those four different cytokines and you get Cox two and that leads to inflammation. All right, the way we stop inflammation today, most people they take ibuprofen, which only affects one of those pathways, right, which is a Cox two pathway, it doesn’t affect the other pathways.
So that’s number one. So this is a beautiful diagram, you can keep in your mind molecular hydrogen hits oxidative stress, again, the literature is here. So this inhibits inflammation, inflammatory genes, inhibits inflammatory enzymes such as coxhoe.
Cocteau’s is an enzyme which creates PG two which actually causes inflammation The next thing is it up regulates antioxidant enzyme heme oxygenase to so this is very valuable because molecular hydrogen will activate this transcription factor NRF two, which is a factor that tells your DNA to go produce this. So NRF two promotes the gene expression of this enzyme H O, one very, very important enzyme, and this is a potent inhibitor of inflammation, H O one very, very important. Number two, the next thing is it prevents the aggregation of immune cells.
So why is that important? Let me explain this. I just talked about molecular hydrogen oxidative stress, and then I went over to molecular hydrogen creates NRF two, which creates this and this H O one blocks inflammation. Now, the other important thing is your aggregation of immune cells.
What does that mean? So let’s say you hit yourself with a hammer, right, your body starts getting inflamed, all the immune cells go there, you definitely want inflammation in that case, because you want your body to repair itself. But the point is, after it’s done with the job, you don’t want them to stay clumped together, because that creates more and more inflammation. You want them to sort of chill out and dissipate.
So in order to do that, you need to make sure that they disaggregate which means go back to their merry ways. So what happens is, if you have the aggregation of neutrophils, it’s going to lead to inflammation. They hang out together too long, like a gang, they get bad habits and they starting fires and everything and oxidative stress promotes this.
But what does molecular hydrogen do? It’s stopping of oxidative stress. Not only does it do this, what we shared here, stop NF Kappa Beta, but it also stops the aggregation of neutrophils. So oxidative stress promotes aggregation, neutrophils and aggregation of neutrophils promotes inflammation, eventually leading to sepsis and organ failure.
So molecular hydrogen brings us down. That’s what this red arrow means it blocks it. And by downregulating, oxidative stress, this molecular hydrogen keeps inflammation under control, very, very valuable healing.
The next thing is it prevents the innate immune cell death. So here’s a macrophage let me explain what a macrophages. So macrophage, remember I said in the immune system, you have these things called the Marines, a macrophage is like a Marine, it’s all a lot of weapons, and he’ll just start going shooting everywhere.
It’s part of the immune system. Well, you obviously don’t want your macrophages dying off because they’re your soldiers. But if they die off, you lose more and more soldiers, your innate immune system gets weakened.
So what molecular hydrogen does, which is also extremely valuable, as we can see right here is that molecular hydrogen, again, everything we’re sharing here, by the way, is coming from the scientific literature which we’ve organized, it’s not like suppositions, the problem with the field, the nutraceuticals. And a lot of the field of supplements is people are just throwing crap out there, no one explains to you how this stuff actually works. What we want to do is take a systems approach actually explain to you how things are actually working so you can become educated you can make from a systems approach a lot more educated knowledge by interconnecting the facts for yourself.
So up here, what we’re looking at is the prevention of the innate immune cell death. So here’s molecular hydrogen and some molecular hydrogen, we’ll stop these two very, very important p 53. If you read about P 53.
It’s extremely involved in cancer, this protein as well as K ask, it’s an acronym. So under inflammatory conditions, proteins, such as as k and p 53, are regulated. So if you want to prevent cancer, and all these things, you don’t want these guys around, and P 53.
Leads to what’s called caspase. And what caspase is, it’s an enzyme which kills your immune cell this like eats away your immune cells. So P 53 leads to caspase K15:00phosphates destroys your immune cells.
Similarly, as k goes to this other pathway called P 38, which creates BCL two, which knocks out caspase. So what does molecular hydrogen do? It blocks p 53. Right? So molecular hydrogen down regulates the activity of this and it down regulates as K, therefore preventing so you’re knocking this out this out.
So this domino effect doesn’t occur. This doesn’t occur until you preserve your macrophage. Does that make sense? We’re going to talk about dosing.
But let me just again, review very quickly, what we’re talking about with molecular hydrogen has multiple effects. It takes out NF Kappa Beta by blocking oxidative stress, it takes out it protects your immune cells, and it makes sure that your immune cells don’t aggregate all of these are very, very important for supporting your immune system. So molecular hydrogen has multiple effects.
That’s why we say when you take a systems approach, it’s not molecular hydrogen is just doing one thing, a lot of the drug therapies like the mRNA vaccine that they just put out, it basically just goes and it’s like just going and trying to generate antibodies where versus the analogy I use imagine orchestra conductor having a huge orchestra, and he just plays the violin all day, okay, nothing else is playing. That’s not a systems approach. A systems approach is when you get infected by a virus or something, your body is tuned to get it through the eyes and the nose and it wakes up the innate immune system and wakes up the interferon, the oboe comes in and the horns come in and everything comes you get this beautiful musical piece that’s called your entire immune system.
And what’s cool about molecular hydrogen, it awakens multiple parts of your immune system. It’s a good orchestra conductor, that’s called the ensemble effect. And from a systems approach, that’s what you want, it’s a good way to understand things that have some very powerful effects, pharmaceutical drugs, it’s gonna have a singular Effect and Cause a side effect more than likely.
So what’s the dosage? Again, this is not a medical program. This is basically to educate you and everything I’m saying here you could go find in the literature, so the maintenance dose according to Fujita at all in 2009 paper, that’s one side of solving our distillation found about point O eight to 1.5 parts per million per day of hydrogen and hydrogen rich water for exercise improvement.
This just came out a couple of years ago, five milligrams a day of hydrogen producing tablets dissolved in water gas inhaled, so basically you take the tablet, put it in the water in a water gas and you inhale it so those are for people exercising for cardiovascular out, this came out about 11 years ago, Niccolo 2010, but 1.5 to two liters of 80% saturated hydrogen water so you want a lot of hydrogen water and you basically you can drink it, but it has a tremendous value for cardiovascular health. So you can see this element has a lot of effects and I think we’re going to see more and more of this coming out the enclosing what I want to share with you.
So when you think about molecular hydrogen, these are the key takeaways. Number one molecular hydrogen promotes strong immune systems by inhibiting inflammatory cytokines that lead to sepsis and runaway host immune systems to it inhibits inflammatory enzymes three it prevents the immune cell aggregation that causes inflammation and the other pieces molecular hydrogen prevents the death of these innate immune cells like macrophages, thereby improving immune response and the this is probably the biggest takeaway. This stuff has very little no known side effects at all.
Alright, everyone, have a good night. Thank you very much. Have a good night.
Bye bye
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